Rely-AMP HHV6
The Herpesviridae is a large family of DNA viruses, including human herpesvirus 6 (HHV-6). Infection with HHV-6 results in exanthem subitum in infants and is associated with severe diseases (encephalitis and pneumonitis) in immunocompromised patients. HHV-6 re-activation causes severe disease in transplant recipients and can lead to graft rejection, often in consort with other betaherpesviridae. Likewise in HIV/AIDS, HHV-6 re-activations cause disseminated infections leading to end organ disease and death.
HHV-6 has been reported in multiple sclerosis patients and has been implicated as a co-factor in several other diseases, including chronic fatigue syndrome and fibromyalgia.
DETAILS
Rely-AMP HHV6 is an in vitro assay for the detection and quantitation of HHV6 viral DNA in human cerebrospinal fluid and whole blood. Rely-AMP HHV6 provides all necessary reagents for reliable extraction and HHV6 DNA detection.
TECHNICAL SPECIFICATIONS
Quantitative/qualitative |
Quantitative
|
Extraction |
Magnetic Resin
|
Technology
|
Real time PCR
|
Sample type |
Cerebrospinal fluid – whole blood
|
Thermal cycler |
optimized with CFX96 (Bio-Rad) but designed for use with real-time devices from various manufacturers
|
Positive control |
HHV6 plasmid DNA
|
Fluorophore
|
FAM
|
Processing |
Manual Automated
|
Time to result |
2 hours (after extraction)
|
PERFORMANCE
Diagnostic sensitivity: 94,5%
Diagnostic specificity: 99,9%
Analytical Specificity: no cross reazione
Analytical sensitivity: 10 copies plasmid
ORDERING INFORMATION
PRODUCT |
CAT.NO. |
PRICE |
Rely-AMP HHV6 extraction and detection kit |
6HHV50 |
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Rely-AMP HHV6 detection kit |
6HHV5D |
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