Rely-AMP HHV6

 

 

The Herpesviridae is a large family of DNA viruses, including  human herpesvirus 6 (HHV-6). Infection with HHV-6 results in exanthem subitum in infants and is associated with severe diseases (encephalitis and pneumonitis) in immunocompromised patients. HHV-6 re-activation causes severe disease in transplant recipients and can lead to graft rejection, often in consort with other betaherpesviridae. Likewise in HIV/AIDS, HHV-6 re-activations cause disseminated infections leading to end organ disease and death.

HHV-6 has been reported in multiple sclerosis patients and has been implicated as a co-factor in several other diseases, including chronic fatigue syndrome and fibromyalgia.

 

 

DETAILS

 

Rely-AMP HHV6 is an in vitro assay for the detection and quantitation of HHV6 viral DNA  in human cerebrospinal fluid and whole blood. Rely-AMP HHV6 provides all necessary reagents for reliable extraction and HHV6 DNA detection.

 

 

TECHNICAL SPECIFICATIONS

 

 

Quantitative/qualitative

 

Quantitative

 

Extraction

 

Magnetic Resin

 

 

Technology

 

 

Real time PCR

 

Sample type

 

Cerebrospinal fluid – whole blood

 

Thermal cycler

 

optimized with CFX96 (Bio-Rad) but designed for use with real-time devices from various manufacturers

 

Positive control

 

HHV6 plasmid DNA

 

 

Fluorophore

 

 

FAM

 

Processing

 

Manual

Automated

 

Time to result

 

2 hours (after extraction)

 

 

 

PERFORMANCE

 

Diagnostic sensitivity:  94,5%

Diagnostic specificity: 99,9%

Analytical Specificity: no cross reazione

Analytical sensitivity: 10 copies plasmid

 

 

ORDERING INFORMATION

 

PRODUCT

CAT.NO.

 PRICE

 

Rely-AMP HHV6 extraction and detection kit

 

6HHV50

 

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Rely-AMP  HHV6 detection kit

 

6HHV5D

 

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