Rely-AMP CMV
Cytomegalovirus (CMV) is a double-stranded DNA virus and is a member of the Herpesviridae family. CMV usually causes an asymptomatic infection or produces mild flulike symptoms. People with compromised immune systems, such as people receiving organ transplants, and people receiving treatment for HIV/AIDS or cancer are at increased risk of serious complications of CMV.
CMV can also cause serious problems if a woman develops a CMV infection during pregnancy, as the infection can spread to the unborn baby . Around one in ten infected babies will have lasting problems: deafness, poor eyesight, intellectual disability, an enlarged liver or spleen, and a small head. Due to the limitations of culture based methods, real-time PCR has become an important laboratory tool for the diagnosis and management of CMV disease.
DETAILS
Rely-AMP CMV is an in vitro assay for the detection of Cytomegalovirus viral DNA in human serum. Rely-AMP CMV provides all necessary reagents for reliable extraction and CMV DNA detection.
TECHNICAL SPECIFICATIONS
Quantitative/qualitative |
Qualitative
|
Extraction |
Magnetic Resin
|
Technology
|
Real time PCR
|
Sample type |
Serum
|
Thermal cycler |
optimized with CFX96 (Bio-Rad) but designed for use with real-time devices from various manufacturers
|
Positive control |
CMV plasmid DNA
|
Fluorophore
|
FAM |
Processing |
Manual Automated
|
Time to result |
2 hours (after extraction)
|
PERFORMANCE
Diagnostic sensitivity: 96%
Diagnostic specificity: 99,9%
Analytical Specificity: 100%
Analytical sensitivity: 10 copies plasmid
ORDERING INFORMATION
PRODUCT |
CAT.NO. |
PRICE |
Rely-AMP CMV extraction and detection kit |
CMV50 |
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Rely-AMP CMV detection kit |
CMV50D |
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