Rely-AMP FACTOR V

Venous Thromboembolism develops as the result of multiple interactions between non-genetic and genetic risk factors.Factor V Leiden is a frequent genetic risk factor involved in venous thromboembolism.

Individuals with factor V Leiden have a mutation at one of the arginine cleavage sites in factor V, such that factor V resists degradation by activated protein C. Persons who are heterozygous or homozygous for this disorder are 8 times and 80 times increased risk, respectively, for VTE.

DETAILS

Rely-AMP FACTOR V  is an in vitro Real Time polymerase chain reaction (RT- PCR) assay to detect mutations factor  V leiden. The assay allows for precise allelic discrimination of homozygous, heterozygous and wild type genotypes. Rely-AMP FACTOR V provides all necessary reagents for reliable extraction and DNA detection.

TECHNICAL SPECIFICATIONS

PERFORMANCE

Diagnostic sensitivity:  >95%

Diagnostic specificity: 100%

Analytical Specificity: no cross reazion

Analytical Sensitivity: 10 copies plasmid

ORDERING INFORMATION