Rely-AMP HBV

 

 

Hepatitis B virus (HBV) is small DNA virus that belongs to the Hepadnaviridae family of viruses. This virus has been known as a common cause of acute and chronic hepatitis infections in humans and may lead to cirrhosis, hepatocellular carcinoma (HCC) and liver failure. The modes of transmission for HBV are sexual contact and other forms of blood exchange (parenteral exposure-horizontal transmission) as well as infection transmitted from mother to child during birth (perinatal-vertical transmission). During the last two decades, serological, virological, biochemical, and histological diagnostic tools are used frequently to monitor and characterize the clinical state of HBV infection. One of the first serologic markers appearing after HBV infection is Hepatitis B surface antigen (HBsAg). Its persistence for more than 6 months reveals chronic HBV infection. Furthermore, serum HBV DNA level indicates the response to antiviral therapy and diagnosis of drug resistance.

 

 

DETAILS

 

Rely-AMP HBV is an in vitro assay for the quantitation of hepatitis B viral DNA in human serum from HBV-infected individuals. Rely-AMP HBV provides all necessary reagents for reliable extraction and HBV DNA detection. The kit is intended to assist the evaluation of the response to antiviral drugs measuring the changes of HCV DNA levels in serum.

 

 

TECHNICAL SPECIFICATIONS

 

 

Quantitative/qualitative

 

Quantitative

 

Extraction

 

Magnetic Resin

 

Technology

 

Real time PCR

 

Sample type

 

Serum

Thermal cycler

 

optimized with CFX96 (Bio-Rad) but designed for use with real-time devices from various manufacturers

 

Fluorophore

 

FAM

Processing

 

Manual

Automated

 

Time to result

 

2 hours (after extraction)

 

 

PERFORMANCE

 

Linear Range of Measurement: 102-107 UI/ml

Analytical sensitivity LOD: 100UI/ml

Analytical Specificity: no cross-reaction

 

 

ORDERING INFORMATION

 

PRODUCT

CAT.NO.

 PRICE

 

Rely-AMP HBV

extraction and detection kit

 

RAB100

 

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